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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPKAPK5
All Species:
18.18
Human Site:
S206
Identified Species:
33.33
UniProt:
Q8IW41
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW41
NP_003659.2
473
54220
S206
R
R
H
Q
K
E
K
S
G
I
I
P
T
S
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102910
666
74053
S401
R
R
H
Q
K
E
K
S
G
I
I
P
T
S
P
Dog
Lupus familis
XP_534678
804
89494
S537
R
R
H
Q
K
E
K
S
G
I
I
P
T
S
P
Cat
Felis silvestris
Mouse
Mus musculus
O54992
473
54134
S206
R
R
H
Q
K
E
K
S
G
I
I
P
T
S
P
Rat
Rattus norvegicus
Q66H84
384
43204
N163
I
Q
F
L
H
S
Q
N
I
A
H
R
D
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521063
278
31941
K63
T
I
P
K
D
M
R
K
K
I
M
T
G
S
F
Chicken
Gallus gallus
Q5F3L1
789
89022
M210
F
C
G
T
I
E
Y
M
A
P
D
I
V
R
G
Frog
Xenopus laevis
NP_001085020
377
43533
I162
Q
Y
L
H
S
I
N
I
A
H
R
D
V
K
P
Zebra Danio
Brachydanio rerio
NP_001002336
471
53898
S206
R
R
H
Q
K
E
K
S
G
I
I
P
T
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49071
359
41383
K144
D
I
A
H
R
D
L
K
P
E
N
L
L
Y
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500006
366
41523
A151
V
T
T
A
S
N
A
A
L
K
L
T
D
F
G
Sea Urchin
Strong. purpuratus
XP_001194739
473
54175
K207
K
R
Q
R
R
E
Q
K
N
L
I
Q
T
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZV15
583
64702
P299
F
T
D
V
V
G
S
P
Y
Y
V
A
P
E
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
70.7
58
N.A.
97.2
34.4
N.A.
57.2
21.1
34
87
N.A.
32.3
N.A.
34.6
56
Protein Similarity:
100
N.A.
70.7
58.3
N.A.
98.7
52.8
N.A.
58.1
35.3
52
94.2
N.A.
49.2
N.A.
52.4
72.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
13.3
6.6
6.6
100
N.A.
0
N.A.
0
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
20
N.A.
33.3
6.6
13.3
100
N.A.
13.3
N.A.
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
8
8
16
8
0
8
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
8
0
0
0
0
8
8
16
0
0
% D
% Glu:
0
0
0
0
0
54
0
0
0
8
0
0
0
8
0
% E
% Phe:
16
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
8
0
0
8
0
0
39
0
0
0
8
0
16
% G
% His:
0
0
39
16
8
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
8
16
0
0
8
8
0
8
8
47
47
8
0
0
0
% I
% Lys:
8
0
0
8
39
0
39
24
8
8
0
0
0
8
8
% K
% Leu:
0
0
8
8
0
0
8
0
8
8
8
8
8
0
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
8
8
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
8
8
8
0
39
8
0
54
% P
% Gln:
8
8
8
39
0
0
16
0
0
0
0
8
0
0
0
% Q
% Arg:
39
47
0
8
16
0
8
0
0
0
8
8
0
8
0
% R
% Ser:
0
0
0
0
16
8
8
39
0
0
0
0
0
54
0
% S
% Thr:
8
16
8
8
0
0
0
0
0
0
0
16
47
0
8
% T
% Val:
8
0
0
8
8
0
0
0
0
0
8
0
16
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
8
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _